Fig. 3

Differentially expressed gene analysis. a The thermal map of enrichment scores of each group in each subgroup. The x-coordinate represents the difference multiple pairs between the two groups, and the y-coordinate represents the difference FDR (Q value)-Log10 value between the two groups. Red was used for expression level upregulation, and blue was used for expression level downregulation. Red and blue dots indicate differences (FDR < 0.05 and more than twofold difference were used as the judging criteria); gray dots indicate no difference in gene expression level. b Differential gene expression heatmap: Each row represents a gene, and each column represents a cell. Cells in the same group in the figure are grouped together, and the group of each cell is marked with contrast above the heatmap. Within each group, cells of the same cell subgroup are grouped together, and each cell belongs to a cell subgroup labeled as a cluster above the heatmap