Fig. 5

KEGG enrichment analysis. a KEGG enrichment circle diagram (The first circle: the top 20 enriched signaling pathways, the outer circle is the coordinate scale of gene number, and different colors represent different A class; Circle 2: the number and Q values of this pathway in background genes. The more genes there are, the longer the bars, the smaller the Q values, and the redder the colors. The third circle: upregulated gene ratio map, dark purple represents upregulated genes, light purple represents downregulated genes, and specific values are displayed at the bottom; and Circle 4: enrichment values of each pathway, i.e., the number of differentially expressed genes in the pathway divided by all the numbers (each grid line in the background represents 0.1). b KEGG enrichment bar graph (ordinate is pathway, and abscis is the percentage of the number of pathways in the number of differentially expressed genes; the smaller the Q value, the darker the color; and the number of pathways and Q value are shown in the column). c Ribosome pathway (red for upregulation). d MAPK signaling pathway