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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Comparison of the ability of exosomes and ectosomes derived from adipose-derived stromal cells to promote cartilage regeneration in a rat osteochondral defect model

Fig. 1

Effect of ASC-Ectos and ASC-Exos on the proliferation, migration, and apoptosis of chondrocytes. PBS treatment served as a control. (a) Representative fluorescence micrograph of EV uptake by chondrocytes. The blue and red colors represent the nucleus and PKH26-labeled EVs, respectively. (b) Chondrocyte viability measured by CCK-8 at 24, 48, and 72 h after co-incubation with EVs. (c) Representative images showing the transwell migration assay and scratch assay of chondrocytes treated with EVs for 24 and 48 h. (d) Quantitative analysis of the migrated chondrocytes. (e) Quantitative analysis of the wound closure. (f) Flow cytometry analysis of apoptosis in chondrocytes with different treatments. (g) Quantitative evaluation of chondrocyte apoptotic rate. Scale bar: 100 μm. *p < 0.05. Data were presented as mean ± SD of three replicates

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Stem Cell Research & Therapy

ISSN: 1757-6512