Fig. 4

Tail-less nuclei formation. Time-lapse imaging revealed that tail-less nuclei are formed by a single nuclear remodelling that occurs as the cell reshapes from a flat to a spherical morphology, positioning the nucleus in a peripheral position within the cell (white arrows). Subsequently, the tail-less nucleus began to move within the hBM-MSC-derived intermediate cells (yellow arrows). Scale bar: 10 μm. The number at the top indicates the time since the time-lapse image began. Elapsed time is displayed in the format (hours:minutes)