Table 2 The behavior and complications of different POI rat models
From: Model construction and drug therapy of primary ovarian insufficiency by ultrasound-guided injection
Group | Social behavior | Appearance | RGS | Hair | Ovaries weight | Complications | Death rate (%) | |||
|---|---|---|---|---|---|---|---|---|---|---|
Orbital tightening | Nose/cheek flattening | Ear changes | Whisker change | |||||||
Control | Active | Normal | 0 | 0 | 0 | 0 | Smooth, lightness | 0.083 ± 0.005 g | / | 0 |
POI-C model | Dispirition | Distress | 2 | 1 | 1 | 0 | Rough, dinginess, | 0.068 ± 0.026 g | Bone marrow suppression; Hepatic nodules; bleeding (Nasal, orbital, Intestine) | 37.5 |
POI-B model | Dispirition | Distress | 1 | 1 | 1 | 0 | Rough, dinginess | 0.07 ± 0.28 g | Urinary retention, bleeding (Nasal, orbital, Intestine) | 40 |
POI-U model | Active | Normal | 0 | 0 | 0 | 0 | Smooth, lightness | 0.074 ± 0.016 | Injured blood vessels | 9 |
MS model | Active | Normal | 0 | 0 | 0 | 0 | Smooth, lightness | 0.089 ± 0.008 g | Mental disorder (Schizophrenia or depression) | 0 |