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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: TC14012 enhances the anti-fibrosis effects of UC-MSCs on the liver by reducing collagen accumulation and ameliorating inflammation

Fig. 1

The CXCR7 gene expression profiles in liver and cells. a and b The Col1A2 gene expression (a) and CXCR7 (b) in liver biopsy samples from cirrhotic patients by online GEO database. c Immunofluorescent staining detected CXCR7 expression in liver. Scale bar: 100 μm. d Western blotting detected CXCR7 expression in primary LSEC from normal and liver fibrotic mice. e UC-MSCs were treated with TC14012, CXCR7 expression in UC-MSCs were examined by Western blotting. f and g After LSEC co-cultured with TC14012-pretreated UC-MSCs for 48 h, CXCR7 expression in LSEC were detected by Western blotting and immunofluorescent staining. Scale bar: 50 μm. Full-length blots are presented in Additional file 1: Fig. S8 The data were presented as the mean ± SD. * p < 0.05, **** p < 0.0001

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