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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Kupffer cells abrogate homing and repopulation of allogeneic hepatic progenitors in injured liver site

Fig. 7

Initial innate immune response collectively eliminate engrafted allo-HPs at early stages. A Experimental design: anti-Ly6G and CLs/PLs were injected 24 h before CI, whereas allo-HPs were engrafted 6 h post-CI. The samples were collected post-24 h allo-HPs engraftment. B Representative images of sham-treated samples post-transplantation. C Isotype—or PLs-treated liver samples are presented. D, E Anti-Ly6G-treated samples representing few allo-HPs at the injured site. F, G CLs-treated samples representing substantially accumulated allo-HPs as compared to D and E. Scale bar 100 µm (inset = 50 µm), n = 3/27

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