Fig. 7

Neuroprotective effects of Hmga2 on retina during SI-induced retinal injury. a A comparison of retinal structures between SI-treated and Hmga2-SI-treated groups using DAPI and Rhodopsin staining. b The mean number of photoreceptor rows along central sections of the retina between SI-treated and Hmga2-SI-treated retinas at various time points (n = 3). c Relative fluorescent intensity of Rhodopsin protein in the central retinas with SI treatment and Hmga2-SI treatment at various time points (n = 3). d ERG waveforms in scotopic conditions between SI-treated and Hmga2-SI-treated retinas at various time points. e A comparison of the a-wave (e1) and b-wave (e2) amplitudes in scotopic conditions between the SI-treated and Hmga2-SI-treated retinas at various time points (n = 6). f The light/dark transition test sketch map (f1) and a comparison of the duration time proportion in the black box between the SI-treated and Hmga2-SI-treated retinas at various time points (f2) (n = 11). ONL Outer nuclear layer, INL Inner nuclear layer, GCL Ganglion cell layer. *P < 0.05; **P < 0.01; ***P < 0.001; # P < 0.05; # # P < 0.01; ### P < 0.001; ▲P < 0.05; ▲▲ P < 0.01,;▲▲▲ P < 0.001. Unpaired t-test was used in (b, c, e, f)