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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model

Fig. 6

Apop-Tag peroxidase immunoreaction. A GMSCs-treated immune-stained section showing apparent low expression of positive apoptotic nuclei of the acinar cells (↑) after irradiation. (Apop Tag, ×400). B The immune-stained section of the radiated parotid gland shows high expression of positive apoptotic nuclei in both the acinar cells (↑) and the ductal cells (arrowheads). (Apop Tag, ×400). C The immune-stained section of normal control parotid salivary gland tissues shows the expression of positive apoptotic nuclei in the acinar cells (↑). (Apop Tag, ×400). D A bar graph showing a significantly higher mean area percentage of Apop-Tag immune positive reaction was recorded at 16 weeks post-irradiation, while there was no significant difference between the GMSCs-treated group and the control group. *** p ≤ 0.001 [IR/GMSCSs] compared to [IR/PBS] group

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Stem Cell Research & Therapy

ISSN: 1757-6512