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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model

Fig. 7

PCNA immunoreaction.A GMSCs-treated immune-stained section showing apparent high expression of positive PCNA nuclei of the ductal cells (arrowheads) as well as, acinar cells (↑) (PCNA, ×400). B The immune-stained section of the radiated parotid gland shows a low expression of PCNA-positive nuclei in the acinar cells (↑). (PCNA, ×400) C The immune-stained section of normal control parotid salivary gland tissues shows the high expression of PCNA-positive nuclei in the acinar cells (↑). D A bar graph showing that the GMSCs-treated group and Control group significantly recorded higher values of mean area percentage of PCNA immune positive reaction, while there was no significant difference between the stem cell group and the control group. *** p ≤ 0.001 [IR/GMSCSs] compared to [IR/PBS] group

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