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Retraction Note: Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat

The Original Article was published on 16 July 2021

Retraction Note: Stem Cell Research & Therapy (2021) 12:409

https://doi.org/10.1186/s13287-021-02429-z

RETRACTION NOTE.

The Editors in Chief have retracted this article after concerns were raised about the data reported. Specifically:

  • In Fig. 7a, there is evidence of a potential splice between lanes 2 and 3 of GAPDH blot.

  • The GAPDH blot of Fig. 11a appears to duplicate the GAPDH blot of Fig. 11c. In Fig. 11c, there is also evidence of a potential splice between lanes 1 and 2 of Galectin 3 blot.

  • In Fig. 15, several panels appear to partially or wholly duplicate one another: the TGF-β1 + DMEM/F12-treated subgroup of control and the TGF-β1 + MSCs-CM-treated subgroup of Gal-3 OE (both α-SMA); the MSCs-CM-treated subgroup of control (E-Cadherin) and the normal subgroup of Gal-3OE (α-SMA); and the TGF-β1 + DMEM/F12-treated subgroup of control (E-Cadherin) and the normal subgroup of control (α-SMA).

The Editors in Chief therefore no longer have confidence in the reliability of the data presented. Bo Chen has stated on behalf of all authors that they agree with the retraction.

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The online version of the original article can be found at https://doi.org/10.1186/s13287-021-02429-z.

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Tang, H., Zhang, P., Zeng, L. et al. Retraction Note: Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat. Stem Cell Res Ther 15, 52 (2024). https://doi.org/10.1186/s13287-024-03668-6

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