Impacts of priming on distinct immunosuppressive mechanisms of mesenchymal stromal cells under translationally relevant conditions

Table 1 Correlation for each priming strategy separately

gene	r	p-value	p/h/3D
CD74	-0.93	< 0.001	p
CXCL9	-0.90	< 0.001	p
IDO1	-0.88	< 0.001	p
ICAM1	-0.87	< 0.001	p
CXCL11	-0.86	< 0.001	p
CCL5	-0.86	< 0.001	p
TNFAIP6	-0.80	< 0.001	p
IL1RN	-0.80	< 0.001	p
CXCL10	-0.80	< 0.001	p
CXCL8	-0.77	< 0.001	p
PDCD1LG2	+ 0.72	0.002	3D
LGALS1	-0.59	0.02	p
CCL2	-0.57	0.03	h
PDCD1LG2	-0.51	0.05	h

Sorted by descending |r|. CCL5 (CC motif chemokine ligand 5), CXCL9 (CXC motif chemokine ligand 9), CXCL10 (CXC motif chemokine ligand 10), CXCL11 (CXC motif chemokine ligand 11), CXCL8 (CXC motif chemokine ligand 8), CD74 (major histocompatibility complex class II invariant chain), IL1RN (interleukin 1 receptor antagonist), PDCD1LG2 (programmed cell death 1 ligand 2), IDO1 (indoleamine 2,3diogygenase 1), CCL2 (CC motif chemokine ligand 2), TNFAIP6 (TNF alpha induced protein 6), LGALS1 (galectin 1), ICAM1 (intercellular adhesion molecule 1). p: pro-inflammatory priming, h: hypoxic priming, 3D: 3D culture priming

ISSN: 1757-6512