Fig. 2

UC/PL-MSC-CM ameliorates inflammation-associated intestinal fibrosis in chronic DSS-induced colitis. A Representative hematoxylin and eosin [H&E] staining of colon sections. B Submucosal thickness (µm). C Muscularis propria thickness (µm). D Representative Sirius red staining of colon sections. E Positive area (%) in Sirius red staining. F Hydroxyproline concentration (µg/mg of protein). Data are expressed as means ± SEM (n = 10–15 in each group). ^##P < .01 and ^###P < .001 versus the control group; ^*P < .05 and.^*** P < .001 versus the DSS group (ANOVA w/ Tukey). Scale bars, 500 µm; original magnification, × 100 (A, D)