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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Transcriptomic and proteomic profiles of fetal versus adult mesenchymal stromal cells and mesenchymal stromal cell-derived extracellular vesicles

Fig. 3

EV concentrations and surface marker expression on the isolated EVs. Nanoparticle tracking analysis (NTA) of extracellular vesicles (EVs), and quantification of proteins on the surface of the EVs by MACSPlex exosome assay. The mode size of (A) fetal EVs (fEVs) and (B) adult EVs (aEVs), as shown in the representative particle and average size distributions using NTA. The median APC fluorescence intensity values for each protein expressed in the EVs are shown. Averaged Size / Concentration Red lines indicate ± 1 standard deviation of the mean. (C) The mean EV mode size distribution of fetal and adult EVs. Surface detection of markers on (D) fEVs and (E) aEVs. Nine independent experiments were performed from each donor (n = 4 biological replicates of fEVs and n = 5 biological replicates of aEVs)

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Stem Cell Research & Therapy

ISSN: 1757-6512