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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Transcriptomic and proteomic profiles of fetal versus adult mesenchymal stromal cells and mesenchymal stromal cell-derived extracellular vesicles

Fig. 6

Enrichment maps of transcriptomic differences between fMSCs and aMSCs. Enrichment maps visualizing the gene set enrichment analysis comparing the transcriptomes of (A) fMSCs and (B) aMSCs using Cytoscape 3.9.1. Individual nodes represent an enriched gene set from C2 or C5 collections with FDR adj-P < 0.05. Blue node colour indicates enrichment in fMSCs and red node colour enrichment in aMSCs. The edges of connecting nodes with overlapping genes in different pathways and the thickness of the green lines reflects the magnitude of overlaps. Several nodes were manually clustered into the yellow circles and labelled to describe overarching biological themes

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