Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Pyrroloquinoline quinone promotes human mesenchymal stem cell-derived mitochondria to improve premature ovarian insufficiency in mice through the SIRT1/ATM/p53 pathway

Fig. 2

PQQ facilitates MSC-Mito proliferation and synergistically MSC-Mito restores mitochondrial function and suppresses oxidative stress. (A) Observation of the quantity of MitoTracker-labelled MSC-Mito in the cells using fluorescence microscopy. (B) Quantitative analysis of MitoTracker-stained MSC-Mito in the cells. (C) Relative expression levels of MSC-Mito DNA in the cells detected using qPCR. (D) In vitro assessment of the impact of MSC-Mito in conjunction with PQQ on ATP production. (E-G) In vitro assessment of the effect of MSC-Mito in conjunction with PQQ on ROS, SOD, and MDA levels. Scale bar: 200 μm. Values are the means ± SEMs. *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512