Fig. 6
From: NANOG controls testicular germ cell tumour stemness through regulation of MIR9-2
Identification of MIR9-2-5p pluripotency targets. (A) Predicted pluripotency targets downregulated in EC or SEM upon MIR9-2-5p expression (edgeR, *FDR < 0.05, compared to scrambled). (B) Genes on chromosome 12p expressed in TGCTs and regulated by MIR9-2-5p (direct target genes are highlighted in the blue central box). (C) qRT-PCR validation of downregulated genes at the chromosome 12p13.31 locus in EC and SEM cells expressing MIR9-2-5p (n = 4; *P < 0.05 compared to the scrambled control, Student’s t-test)