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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: A first-in-human clinical study of laparoscopic autologous myoblast sheet transplantation to prevent delayed perforation after duodenal endoscopic mucosal dissection

Fig. 5

Myoblast sheet transplantation after ESD in case 3. A: At least four micro perforations were evident after duodenal ESD. B: Laparoscopy also revealed micro perforations with bile leakage. The thinned duodenal wall was protruding like the diverticulum due to mucosal clipping. C: All micro perforations were completely sealed by transplanted myoblast sheets. D: Abdominal CT three days after transplantation showed a small air bubble with diverticulum-like protrusion of the duodenal wall. Fluid collection around the duodenum was not evident. E: Endoscopy seven days after transplantation revealed an opening of the mucosa with dropout of intraoperative clipping. F: Abdominal CT seven days after transplantation showed air bubbles along the duodenal wall, but they had not extended even after endoscopic observation

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