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Table 3 Clinical and operative characteristics and outcomes

From: A first-in-human clinical study of laparoscopic autologous myoblast sheet transplantation to prevent delayed perforation after duodenal endoscopic mucosal dissection

 

Case 1

Case 2

Case 3

Preoperative evaluation

   

 Tumor size (mm)

22

25

24

 Tumor location

1st~2nd portion

2nd portion

2nd portion

  

distal side of the papilla

distal side of the papilla

Total cell number

1.55 × 108

1.80 × 108

1.32 × 108

 CD56-positive cells (%)

95

98

98

 Cellular viability (%)

98

97

95

ESD

   

Size of resected tumor (mm)

34 × 25

41 × 22

37 × 25

 Size of mucosal defect (mm)

43 × 31

43 × 30

51 × 40

 Mucosal closure

complete

incomplete

complete

 Intraoperative microperforation

no

no

yes, multiple

 Number of transplanted sheets

2

2

2

Resected specimens

   

 en bloc resection

yes

yes

yes

 Histology

adenoma

adenocarcinoma

adenocarcinoma

 Vessel invasion

-

none

none

Postoperative course

   

 Peritonitis

no

yes

yes

 Patient’s condition

stable

stable

stable

 Hospital stay (days)

9

19

17

 Duodenal stenosis after 7 weeks

no

no

no