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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology

Fig. 2

Characterization of cerebral organoids (COs) generated from CmC, CA, and CAP human embryonic stem cell (hESC) lines. (a) Seventy-day-old CmC, CA, and CAP COs derived from the CmC, CA, and CAP hESC lines, respectively. (b) Representative hematoxylin and eosin-stained sections from the CmC, CA, and CAP COs. Scale bar = 500 μm. (c-e) Immunohistochemistry staining for various neuronal markers in the CmC, CA, and CAP COs: SOX2 (red), TUJ1 (green), TBR2 (green), PAX6 (red), MAP2 (green), DCX (green), and neural-specific N-cadherin (green). DAPI indicates the nuclei location (blue). Scale bar = 100 μm

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Stem Cell Research & Therapy

ISSN: 1757-6512