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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status

Figure 2

Characterization of pre-excised and post-excised induced pluripotent stem cell lines. (A) Expression of pluripotency markers from induced pluripotent stem cells (iPSCs) (human embryonic stem cells and parental fibroblasts from which the pre-excised iPSC line was derived serving as controls), showing similar expression of all markers before and after hSTEMCCA excision. (B) Histological analysis of teratomas derived from the pre-excised iPSC parental line and post-excised iPSC line. (C) G-band karyotyping analysis of the post-excised iPSC line, showing a normal 46XY karyotype following excision of hSTEMCCA. Bars = 100 μM.

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Stem Cell Research & Therapy

ISSN: 1757-6512