| MNC | MNC + BM-MSCs | MNC + UCM-MSCs | MNC + AT-MSCs | MNC + PHA | MNC + PHA + BM-MSCs | MNC + PHA + UCM-MSCs | MNC + PHA + AT-MSCs | |
---|---|---|---|---|---|---|---|---|---|
Cell type | Subpopulation | n = 17 | n = 5 | n = 7 | n = 5 | n = 17 | n = 5 | n = 7 | n = 5 |
Total T cells |  | 82 ± 5 | 80 ± 11 | 80 ± 7 | 86 ± 5 | 86 ± 3 | 79 ± 8 | 71 ± 17 | 86 ± 5 |
CD4 + T cells |  | 81 ± 5 | 81 ± 9 | 77 ± 9 | 84 ± 3 | 77 ± 3 | 84 ± 7 | 67 ± 8 | 76 ± 10 |
 | CD69-CD25-HLA-DR- | 100 ± 0 | 100 ± 0 | 99 ± 2 | 100 ± 0 | 25 ± 7 | 23 ± 8 | 18 ± 9 | 43 ± 17a; b; c; d |
 | CD69+CD25-HLA-DR- | 0 ± 0 | 0 ± 0 | 1 ± 2 | 0 ± 0 | 6 ± 1 | 14 ± 4a; d | 15 ± 8a; d | 13 ± 1a; d |
 | CD69+CD25+HLA-DR- | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 67 ± 7 | 58 ± 6a | 66 ± 17 | 43 ± 18a; d |
 | CD69+CD25+HLA-DR+ | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 3 ± 2 | 4 ± 2 | 2 ± 2 | 1 ± 0 |
CD8 + T cells |  | 19 ± 5 | 19 ± 9 | 23 ± 9 | 14 ± 3 | 23 ± 3 | 16 ± 7 | 33 ± 8 | 24 ± 10 |
 | CD69-CD25-HLA-DR- | 99 ± 0 | 99 ± 2 | 98 ± 3 | 100 ± 1 | 18 ± 10 | 22 ± 3 | 12 ± 1b | 41 ± 12a; b; c; d |
 | CD69+CD25-HLA-DR- | 1 ± 0 | 1 ± 2 | 2 ± 2 | 0 ± 1 | 9 ± 1 | 16 ± 4a; d | 18 ± 9a; d | 14 ± 2a |
 | CD69+CD25+HLA-DR- | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 68 ± 11 | 59 ± 6a | 67 ± 10 | 45 ± 14a; b; c; d |
 | CD69+CD25+HLA-DR+ | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 4 ± 2 | 2 ± 3d | 2 ± 2 | 1 ± 1 |
B cell |  | 2 ± 0 | 2 ± 1 | 4 ± 4 | 3 ± 2 | 3 ± 1 | 4 ± 1 | 4 ± 3 | 3 ± 2 |
 | CD69-CD25- | 98 ± 1 | 95 ± 4 | 97 ± 3 | 98 ± 1 | 40 ± 6 | 63 ± 23 | 37 ± 9 | 72 ± 15a; d |
 | CD69+CD25- | 2 ± 1 | 5 ± 4 | 3 ± 3 | 2 ± 1 | 56 ± 7 | 32 ± 15d | 60 ± 6b | 27 ± 14a; d |
 | CD69+CD25+ | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 4 ± 3 | 5 ± 10 | 4 ± 4 | 1 ± 1 |
Total NK cells |  | 16 ± 5 | 19 ± 10 | 16 ± 5 | 12 ± 5 | 12 ± 2 | 20 ± 9 | 20 ± 9 | 11 ± 5 |
CD56 bright NK cells |  | 3 ± 1 | 2 ± 1 | 3 ± 2 | 4 ± 3 | 8 ± 0 | 6 ± 3 | 6 ± 5 | 8 ± 4 |
 | CD69-CD25- | 99 ± 0 | 99 ± 1 | 99 ± 3 | 100 ± 1 | 82 ± 2 | 94 ± 2a; d | 80 ± 20 | 97 ± 1a; b; d |
 | CD69+CD25- | 1 ± 0 | 1 ± 1 | 1 ± 3 | 0 ± 1 | 17 ± 2 | 6 ± 2a; d | 18 ± 17 | 3 ± 1a; b; d |
 | CD69+CD25+ | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 1 ± 0 | 1 ± 0 | 2 ± 3 | 1 ± 0 |
CD56 dim NK cells |  | 97 ± 1 | 98 ± 1 | 97 ± 2 | 96 ± 3 | 92 ± 0 | 94 ± 3 | 94 ± 3 | 92 ± 4 |
 | CD69-CD25- | 97 ± 2 | 96 ± 7 | 97 ± 4 | 99 ± 1 | 29 ± 3 | 73 ± 18a; d | 74 ± 6a; d | 79 ± 19a; d |
 | CD69+CD25- | 3 ± 2 | 4 ± 7 | 3 ± 4 | 1 ± 1 | 68 ± 2 | 25 ± 17a; d | 25 ± 6a; d | 20 ± 19a; d |
 | CD69+CD25+ | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 3 ± 0 | 1 ± 1 | 1 ± 1 | 1 ± 0 |