Figure 2From: Quantitative proteomic analysis of sphere-forming stem-like oral cancer cellsWestern blot analysis of CD44, octamer-binding transcription factor 4 (OCT4), sex determining region Y-box 2 (SOX2), SOX9, transketolase (TKT), hypoxia-inducible factor 1 alpha (HIF-α) and phosphoglycerate kinase 1 (PGK-1) in CSC-like and non-CSC UM1 cells (A). The normalized levels of all seven proteins are shown in (B). Stem cell markers CD44, OCT4, SOX2 and SOX9 were up-regulated in CSC-like UM1 cells whereas HIF-α and PGK-1 were down-regulated in CSC-like cells when compared to non-CSC UM1 cells (n = 3). No significant difference in expression was observed for TKT. *, P <0.05; **, P <0.01. CSC, cancer stem cells.Back to article page