Skip to main content
Figure 2 | Stem Cell Research & Therapy

Figure 2

From: microRNA-378 promotes mesenchymal stem cell survival and vascularization under hypoxic–ischemic conditions in vitro

Figure 2

microRNA-378 transfection reduced hypoxia-induced apoptosis in mesenchymal stem cells. (A) Apoptosis of mesenchymal stem cells (MSCs) was detected and assessed by terminal deoxynucleotidyl transferase biotin-dUPT nick end-labeling (TUNEL) staining. lane a, DAPIr staining localization; lane b, TUNEL staining; lane c, overlap figure of lanes a and b. (B) Comparison of apoptotic rates between groups after miR-378 transfection in normoxic and hypoxic environments. *P < 0.05, **P < 0.01. Native MSCs, MSCs cultured in normoxic conditions; miR-378, miR-378-transfected MSCs cultured in normoxic conditions; MSCs + hypoxia, MSCs cultured in hypoxic conditions; miR-378 + hypoxia, miR-378-transfected MSCs cultured in hypoxic conditions.

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512