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Figure 4 | Stem Cell Research & Therapy

Figure 4

From: Stimulation of Activin A/Nodal signaling is insufficient to induce definitive endoderm formation of cord blood-derived unrestricted somatic stem cells

Figure 4

Sox17 mRNA levels following combined Activin A and FGF4 induction. Sox17 mRNA levels for untreated and Activin A and Fibroblast Factor 4 treated USSC lines and untreated, spontaneously differentiated and Activin A treated hESC. Sox17 mRNA levels were very low in untreated USSC cultured in SCPM or PIM and in USSC lines treated with Activin A and Fibroblast Factor 4. Sox17 mRNA levels were low in untreated hESC, and significantly up-regulated in Activin A treated hESC and in spontaneously differentiated hESC.

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