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Figure 1 | Stem Cell Research & Therapy

Figure 1

From: CCR5 facilitates endothelial progenitor cell recruitment and promotes the stabilization of atherosclerotic plaques in ApoE−/− mice

Figure 1

CCL5 expression in ascending aorta of humans and mice. (A) Immunohistochemistry of CCL5 in non-diseased artery, advanced plaques, and unstable plaques of human samples. (B) Quantitative analysis of CCL5 expression in (A) (n = 3, *P <0.05, **P <0.01). (C) Immunohistochemistry of CCL5 in non-diseased artery, advanced plaques, and unstable plaques of ApoE−/− mice. (D) Quantitative analysis of CCL5 expression in (C) (n = 3, *P <0.05, **P <0.01). Bars represent mean ± standard deviation. ApoE, apolipoprotein E; CCL5, chemokine (C-C motif) ligand 5; IPH, thin capped fibroatheroma with intraplaque hemorrhage (advanced unstable plaques); ND, non-diseased arteries; n.s., non-significant; TfcA, thick fibrous cap atheroma (advanced stable plaques).

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Stem Cell Research & Therapy

ISSN: 1757-6512