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  1. Content type: Review

    The production of veritable in-vitro models of bone tissue is essential to understand the biology of bone and its surrounding environment, to analyze the pathogenesis of bone diseases (e.g., osteoporosis, oste...

    Authors: Alessandro Pirosa, Riccardo Gottardi, Peter G. Alexander and Rocky S. Tuan

    Citation: Stem Cell Research & Therapy 2018 9:112

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  2. Content type: Research

    Silicosis has been topping the list of high-incidence occupational diseases in developing countries and cannot be completely cured. Recent advances in stem cell research have made possible the treatment of var...

    Authors: Shangya Chen, Guanqun Cui, Cheng Peng, Martin F. Lavin, Xiaoying Sun, Enguo Zhang, Ye Yang, Yingjun Guan, Zhongjun Du and Hua Shao

    Citation: Stem Cell Research & Therapy 2018 9:110

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  3. Content type: Research

    Currently, the overall therapeutic efficiency of mesenchymal stem cells (MSCs) transplantation for the treatment of cardiovascular disease is not satisfactory. The low viability and angiogenic capacity of the ...

    Authors: Jingying Hou, Lingyun Wang, Quanhua Wu, Guanghui Zheng, Huibao Long, Hao Wu, Changqing Zhou, Tianzhu Guo, Tingting Zhong, Lei Wang, Xuxiang Chen and Tong Wang

    Citation: Stem Cell Research & Therapy 2018 9:109

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  4. Content type: Correction

    The original article [1] mistakenly omitted a source of funding, and the authors would like to rectify this by acknowledging the additional support of the Natural Science Foundation in Jiangsu Province (BK2015...

    Authors: Zhaoyu Lin, Fei Liu, Peiliang Shi, Anying Song, Zan Huang, Dayuan Zou, Qin Chen, Jianxin Li and Xiang Gao

    Citation: Stem Cell Research & Therapy 2018 9:111

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    The original article was published in Stem Cell Research & Therapy 2018 9:47

  5. Content type: Short report

    Senolytic drugs are thought to target senescent cells and might thereby rejuvenate tissues. In fact, such compounds were suggested to increase health and lifespan in various murine aging models. So far, effect...

    Authors: Clara Grezella, Eduardo Fernandez-Rebollo, Julia Franzen, Mónica Sofia Ventura Ferreira, Fabian Beier and Wolfgang Wagner

    Citation: Stem Cell Research & Therapy 2018 9:108

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  6. Content type: Research

    Platelet-rich plasma (PRP) is an autologous blood product that contains a high concentration of several growth factors. Platelet-derived growth factor (PDGF)-BB is a potential mitogen for human adipose-derived...

    Authors: Fangyuan Lai, Natsuko Kakudo, Naoki Morimoto, Shigeru Taketani, Tomoya Hara, Takeshi Ogawa and Kenji Kusumoto

    Citation: Stem Cell Research & Therapy 2018 9:107

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  7. Content type: Research

    The role of bone tissue engineering in the field of regenerative medicine has been a main research topic over the past few years. There has been much interest in the use of three-dimensional (3D) engineered sc...

    Authors: Francesca Diomede, Agnese Gugliandolo, Paolo Cardelli, Ilaria Merciaro, Valeria Ettorre, Tonino Traini, Rossella Bedini, Domenico Scionti, Alessia Bramanti, Antonio Nanci, Sergio Caputi, Antonella Fontana, Emanuela Mazzon and Oriana Trubiani

    Citation: Stem Cell Research & Therapy 2018 9:104

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  8. Content type: Review

    Damage of mitochondria in the initial period of tissue injury aggravates the severity of injury. Restoration of mitochondria dysfunction and mitochondrial-based therapeutics represent a potentially effective t...

    Authors: Jingyu Wang, Heyangzi Li, Ying Yao, Tengfei Zhao, Ying-ying Chen, Yue-liang Shen, Lin-lin Wang and Yongjian Zhu

    Citation: Stem Cell Research & Therapy 2018 9:106

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  9. Content type: Review

    The fibrocyte, which was first described in 1994, is a type of circulating mesenchymal progenitor cell in the peripheral blood. Fibrocytes play important roles in chronic inflammation, wound healing, tissue re...

    Authors: Feng Zhang, Ke Liu, Han Zhao and Yan He

    Citation: Stem Cell Research & Therapy 2018 9:105

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  10. Content type: Research

    White smoke inhalation (WSI) is an uncommon but potentially deadly cause of acute lung injury and acute respiratory distress syndrome for which no effective pharmaceutical treatment has been developed. This st...

    Authors: Pei Cui, Haiming Xin, Yongming Yao, Shichu Xiao, Feng Zhu, Zhenyu Gong, Zhiping Tang, Qiu Zhan, Wei Qin, Yanhua Lai, Xiaohui Li, Yalin Tong and Zhaofan Xia

    Citation: Stem Cell Research & Therapy 2018 9:101

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  11. Content type: Research

    Understanding stem cell behavior as a delivery tool in cancer therapy is essential for evaluating their future clinical potential. Previous in-vivo studies proved the use of mesenchymal stem cells (MSCs) for l...

    Authors: Hamideh Salehi, Siham Al-Arag, Elodie Middendorp, Csilla Gergely, Frederic Cuisinier and Valerie Orti

    Citation: Stem Cell Research & Therapy 2018 9:103

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  12. Content type: Research

    Human decidua parietalis mesenchymal stem/multipotent stromal cells (DPMSCs) have unique phenotypic and functional properties that make them promising candidates for cell-based therapy. Here, we investigated DPMS...

    Authors: M. H. Abumaree, E. Bahattab, A. Alsadoun, A. Al Dosaimani, F. M. Abomaray, T. Khatlani, B. Kalionis, M. F. El-Muzaini, A. O. Alawad and A. S. AlAskar

    Citation: Stem Cell Research & Therapy 2018 9:102

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  13. Content type: Research

    With the development of osteoimmunology and bone tissue engineering (BTE), it has been recognized that the immunomodulatory properties of bone biomaterials have considerable impact in determining their fate af...

    Authors: Tao Li, Zhong Long Liu, Ming Xiao, Ze Zheng Yang, Ming Zheng Peng, Cui Di Li, Xiao Jun Zhou and Jin Wu Wang

    Citation: Stem Cell Research & Therapy 2018 9:100

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  14. Content type: Research

    Commitment of pluripotent stem cells into differentiated cells and associated gene expression necessitate specific epigenetic mechanisms that modify the DNA and corresponding histone proteins to render the chr...

    Authors: Varsha Pursani, Deepa Bhartiya, Vivek Tanavde, Mohsin Bashir and Prabha Sampath

    Citation: Stem Cell Research & Therapy 2018 9:97

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  15. Content type: Research

    It is currently unknown if the intrathecal administration of a high dose of allogeneic mesenchymal stem cells (MSCs) is safe, how MSCs migrate throughout the vertebral canal after intrathecal administration, a...

    Authors: Danielle Jaqueta Barberini, Monica Aleman, Fabio Aristizabal, Mathieu Spriet, Kaitlin C. Clark, Naomi J. Walker, Larry D. Galuppo, Rogério Martins Amorim, Kevin D. Woolard and Dori L. Borjesson

    Citation: Stem Cell Research & Therapy 2018 9:96

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  16. Content type: Research

    Mesenchymal stem cells have potential applications in inflammatory bowel disease due to their immunomodulatory properties. Our aim was to evaluate the feasibility, safety and efficacy of endoscopic administrat...

    Authors: Eduardo Martín Arranz, María Dolores Martín Arranz, Tomás Robredo, Pablo Mancheño-Corvo, Ramón Menta, Francisco Javier Alves, Jose Manuel Suárez de Parga, Pedro Mora Sanz, Olga de la Rosa, Dirk Büscher, Eleuterio Lombardo and Fernando de Miguel

    Citation: Stem Cell Research & Therapy 2018 9:95

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  17. Content type: Research

    Nicotine has negative effects on tissue repair, little research concerns its effect on the cartilage repair of tissue engineering stem cells. The present study aimed to investigate the effects of nicotine on t...

    Authors: Kai Tie, Min Wu, Yu Deng, Yinxian Wen, Dan Xu, Liaobin Chen and Hui Wang

    Citation: Stem Cell Research & Therapy 2018 9:98

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  18. Content type: Short report

    Bullosis diabeticorum is a rare presentation of cutaneous manifestation most commonly affecting the lower limbs in patients with diabetes. The appearance, often as insidious as its resolution, is characterized...

    Authors: Yan Chen, Yu Ma, Ning Li, Hongyan Wang, Bing Chen, Ziwen Liang, Rui Ren, Debin Lu, Johnson Boey, David G. Armstrong and Wuquan Deng

    Citation: Stem Cell Research & Therapy 2018 9:99

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  19. Content type: Research

    Upon orthognathic mandibular advancement surgery the adjacent soft tissues can displace the distal bone segment and increase the load on the temporomandibular joint causing loss of its integrity. Remodeling of...

    Authors: Ricardo de Souza Tesch, Esther Rieko Takamori, Karla Menezes, Rosana Bizon Vieira Carias, Cláudio Leonardo Milione Dutra, Marcelo de Freitas Aguiar, Tânia Salgado de Sousa Torraca, Alexandra Cristina Senegaglia, Cármen Lúcia Kuniyoshi Rebelatto, Debora Regina Daga, Paulo Roberto Slud Brofman and Radovan Borojevic

    Citation: Stem Cell Research & Therapy 2018 9:94

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  20. Content type: Research

    Inflammatory bowel disease (IBD) is an intractable autoimmune disorder that markedly deteriorates one’s quality of life. Mesenchymal stem cells (MSCs) alleviate inflammation by modulating inflammatory cytokine...

    Authors: Woo-Jin Song, Qiang Li, Min-Ok Ryu, Jin-Ok Ahn, Dong Ha Bhang, Yun Chan Jung and Hwa-Young Youn

    Citation: Stem Cell Research & Therapy 2018 9:91

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  21. Content type: Research

    Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive muscle weakness, paralysis and death. There is no effective treatment for ALS and stem cell therapy has arisen a...

    Authors: Amaya Rando, Diego Pastor, Mari Carmen Viso-León, Anna Martínez, Raquel Manzano, Xavier Navarro, Rosario Osta and Salvador Martínez

    Citation: Stem Cell Research & Therapy 2018 9:90

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  22. Content type: Research

    Replacement therapy for hemophilia remains a lifelong treatment. Only gene therapy can cure hemophilia at a fundamental level. The clustered regularly interspaced short palindromic repeats–CRISPR associated nu...

    Authors: Cuicui Lyu, Jun Shen, Rui Wang, Haihui Gu, Jianping Zhang, Feng Xue, Xiaofan Liu, Wei Liu, Rongfeng Fu, Liyan Zhang, Huiyuan Li, Xiaobing Zhang, Tao Cheng, Renchi Yang and Lei Zhang

    Citation: Stem Cell Research & Therapy 2018 9:92

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  23. Content type: Research

    Mesenchymal stem cells (MSCs) are multipotent cells holding much promise for applications in regenerative medicine. However, with problems such as aging, increases in heteroploid cells, genomic instability, an...

    Authors: Koichi Fujisawa, Kazusa Hara, Taro Takami, Sae Okada, Toshihiko Matsumoto, Naoki Yamamoto and Isao Sakaida

    Citation: Stem Cell Research & Therapy 2018 9:93

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  24. Content type: Research

    Previous studies have reported that transplantation of mesenchymal stem cells (MSCs) from many human tissues could ameliorate ovarian dysfunction. However, no study has revealed the therapeutic efficiency of M...

    Authors: Jun Li, Qingtong Yu, Haisen Huang, Wenwen Deng, Xia Cao, Michael Adu-Frimpong, Jiangnan Yu and Ximing Xu

    Citation: Stem Cell Research & Therapy 2018 9:81

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