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Figure 8 | Stem Cell Research & Therapy

Figure 8

From: CCR5 facilitates endothelial progenitor cell recruitment and promotes the stabilization of atherosclerotic plaques in ApoE−/− mice

Figure 8

Effects of CCL5 and CCR5 interaction on endothelial progenitor cell (EPC) migration and proliferation. (A) Transwell migration assay of EPCs after transfection with Lenti-EGFP or Lenti-CCR5. (B) Quantitative analysis of the results in (A) (n = 3, *P <0.05, **P <0.01). (C) Representative images of 5-ethynyl-2′-deoxeuridine (EdU) cell proliferation after transfection with Lenti-EGFP or Lenti-CCR5. Arrows indicate EdU-positive cells. (D) Rate of EdU-positive cells in (C) (n = 3). Bars represent mean ± standard deviation. CCL5, chemokine (C-C motif) ligand 5; CCR5, chemokine (C-C motif) receptor 5; DAPI, 4′, 6-diamidino-2-phenylindole; EGFP, enhanced green fluorescent protein; n.s., non-significant.

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Stem Cell Research & Therapy

ISSN: 1757-6512