Figure 1
From: Sdf-1 (CXCL12) induces CD9 expression in stem cells engaged in muscle regeneration
Sdf-1 impact on the expression of adhesion proteins in regenerating rat soleus muscle. (A) Quantitative RT-PCR analysis of mRNAs encoding m-cadherin, ADAM-12, syndecan-4, CD9, CD81, integrin β1 (itgb1), integrin α3 (itga3), integrin α7 (itga7), and integrin α9 (itga9) in control and Sdf-1-treated muscles (Sdf-1) at days 1 and 3 of regeneration. (B) Immunolocalisation of m-cadherin, ADAM-12, itga9, and CD9 in control and Sdf-1-treated muscles at day 3 of regeneration. Bar = 50 μm. (C) Immunolocalisation of CD9 in control and Sdf-1-treated muscles at day 7 of regeneration. (D) Level of m-cadherin, itga9, and CD9 protein during control (ctrl) and Sdf-1-treated muscle regeneration at days 1, 3, and 7 (C – intact muscle). *P <0.05. Error bars indicate standard deviation.