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Table 5 Expression of canonical pathway-related genes (χ±s)

From: Expression of Wnt and Notch signaling pathways in inflammatory bowel disease treated with mesenchymal stem cell transplantation: evaluation in a rat model

Group

Number

Wnt3a

Fzd3

GSK-3β

APC

β-catenin

TCF4

C-myc

Cyclin D

MSCs

3

0.01±0.01b,c

0.12±0.01b,c

0.70±0.06b

0.36±0.01b,c

0.65±0.17c

0.35±0.01b,c

2.60±0.17b

2.39±0.13b,c

Normal

6

1.00±0.01a,c

1.00±0.01a

1.00±0.01c

1.00±0.01a

1.00±0.01c

1.00±0.01a

1.00±0.01a

1.00±0.01a

14-day IBD

3

2.44±0.63a,b

1.05±0.37a

0.62±0.04b

0.63±0.04a,b

1.58±0.32a,b

1.16±0.30a

1.64±0.32

0.61±0.24a,b

14-day MSCT

3

0.15±0.05a-c

0.35±0.07a-c

0.81±0.07c

0.53±0.07b

1.37±0.34a

0.71±0.09a-c

2.00±0.01b

0.72±0.07a

28-day IBD

3

3.40±1.05a,b

1.34±0.15a

0.68±0.01b

1.05±0.01a

1.93±0.55a,b

1.12±0.22a

1.20±0.58

1.40±0.10a

28-day MSCT

3

0.14±0.02a-c

0.65±0.06a-c

0.78±0.11c

0.96±0.13

0.82±0.17c

0.76±0.14a-c

0.31±0.10a-c

0.18±0.07a-c

  1. a P <0.05 versus mesenchymal stem cell (MSC) group; b P <0.05 versus normal group; c P <0.05 versus inflammatory bowel disease (IBD) group. MSCT, mesenchymal stem cell transplantation