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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human amniotic mesenchymal stromal cells (hAMSCs) as potential vehicles for drug delivery in cancer therapy: an in vitro study

Fig. 4

Evaluation of paclitaxel (PTX) internalized by human amniotic mesenchymal stromal cells (hAMSCs) but not released into culture medium. a Proliferation curves of CFPAC-1 in the presence of serial dilutions of conditioned media from PTX-primed hAMSCs (hAMSCsPTX-CM) (solid line) or lysates from PTX-primed hAMSCs (hAMSCsPTX-LYS) (dashed line). Five different hAMSC donors were tested. b The graph shows the amount of PTX incorporated and released by hAMSCs (CM) and the amount incorporated and retained inside the cells (LYS), expressed as percentages of the total incorporated PTX, considered 100 %. Bars represent the mean values ± SD. Five different hAMSC donors were tested. The difference between CM and LYS was not statistically significant (p >0.05)

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