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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Human amniotic epithelial cells inhibit granulosa cell apoptosis induced by chemotherapy and restore the fertility

Fig. 2

Chemotherapy-induced apoptosis of granulosa cells within developing follicle. A TUNEL-positive cells were observed in the ovary tissue at 7 days after chemotherapy. The red stain indicates TUNEL-positive granulosa cells. The blue DAPI stain indicates the cell nucleus. B Relative expression of Bcl2, Bax and TNF-α mRNA in ovarian tissue at 3, 7 and 10 days after chemotherapy. Data represent means ± SEM; *p < 0.05 versus Sham. Scale bar = 200 μm (a, b, c and d), 100 μm (e and f). Sham sham group (n = 6), Cy-3days chemoablated 3-day group (n = 6), Cy-7days chemoablated 7-day group (n = 6), Cy-10days chemoablated 10-day group (n = 6)

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Stem Cell Research & Therapy

ISSN: 1757-6512