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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Induced pluripotent stem cell models of Zellweger spectrum disorder show impaired peroxisome assembly and cell type-specific lipid abnormalities

Fig. 5

OPCs and mature OLs derived from PBD-ZSD patient and healthy control iPSCs. a Images of OPCs derived from the indicated patient (top row) and healthy control (bottom row) donor immunostained for the OPC markers, PDGFRα and SOX10. b Images of OLs derived from the indicated patient and healthy control donors immunostained for O4 without (left) and with (right) bright field staining. c Images of mature OLs derived from the indicated patient (top row) and healthy control (bottom row) immunostained for myelin basic protein (MBP) and O4 using the same magnification. Arrows indicate patient cell that is positive for MBP and O4. Blue color represents DAPI nuclear counterstaining in all cases

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Stem Cell Research & Therapy

ISSN: 1757-6512