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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Polyphenols from marine brown algae target radiotherapy-coordinated EMT and stemness-maintenance in residual pancreatic cancer

Fig. 5

a QPCR analysis showing mRNA levels of EIF4C, OCT3/4, Nanog, LIF, and ZIC3 in ALDH+CD44+CD24+ PC-CSCs derived from xenografts of Panc-1 and MiaPaCa-2, either mock irradiated or exposed to FIR, with or without 100 μg/ml SA-EA, PT-EA, or HT-EA. b Representative immunoblots showing expression levels of Nanog, Sox2, and Oct3/4 in Panc-1, MiaPaCa-2, Panc-3.27, and BXPC-3-derived ALDH+CD44+CD24+ PC-CSCs, either mock irradiated or exposed to radiation, with or without SA-EA, PT-EA, or HT-EA. c Histograms show the Quantity-One densitometry of relative band intensities. ALDH aldehyde dehydrogenase, ANOVA analysis of variance, CSC cancer stem cell, FIR fractionated irradiation, HT-EA ethyl acetate polyphenol fraction of Hormophysa triquerta, PC pancreatic cancer, PT-EA ethyl acetate polyphenol fraction of Padina tetrastromatica, SA-EA ethyl acetate polyphenol fraction of Spatoglossum asperum

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Stem Cell Research & Therapy

ISSN: 1757-6512