Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Differentially expressed microRNAs in bone marrow mesenchymal stem cell-derived microvesicles in young and older rats and their effect on tumor growth factor-β1-mediated epithelial-mesenchymal transition in HK2 cells

Fig. 2

Age-dependent changes in miRNA profiles of young and old MVs. a Expression of miRNAs in young and old MVs and mapping of hierarchic clustering of miRNAs and heatmap display of miRNA profiles. b Significant fold changes in miRNAs (fold change > 1.5) in old MVs versus young MVs. Upregulated miRNAs were marked in red, and downregulated miRNAs are indicated in green. c RT-PCR analysis was used to validate the downregulated miRNAs in young and old MVs. d RT-PCR analysis was employed to validate the downregulated miRNAs in serum from young and old rats (*P < 0.05; **P < 0.01; n = 5). miRNA microRNA, MV microvesicle, RT-PCR reverse transcription-polymerase chain reaction

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512