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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Genetic modification of human mesenchymal stem cells helps to reduce adiposity and improve glucose tolerance in an obese diabetic mouse model

Fig. 8

a (left panel) and b (right panel): Mitosox Red dye assay for detection and quantification of mitochondria generated reactive oxygen species presence intra-cellularly: Post culture at day 7 in NG and HG. Left panel: ADMSCs plated in normal glucose (NG, 5.5 mM), Right panel: ADMSCs plated in high glucose (HG, 25 mM). The fluorescence peaked at day 7 of culture and decayed beyond 14 days. Magnification: 10×. c Showing relative MitoSox fluorescence of normal glucose vs high glucose exposed cells over two weeks. NG normal glucose, HG high glucose, ADMSCs adipose tissue derived mesenchymal stem cells

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Stem Cell Research & Therapy

ISSN: 1757-6512