Fig. 5

Electron micrographs illustrating ultrastructural characteristics of EC-MSCs at P1 and neuron-like cells derived from cultured EC-MSCs at P3. EC-MSCs at P1 have large nuclei (N), prominent nucleoli (NU), small pseudopodia-like processes at the cell periphery (arrow) (a). Dilated rough endoplasmic reticulum (arrows) (b) and Golgi complexes (arrow) (c) were present in cytoplasm. Tight junctions were seen in the periphery (arrow) (d). Neuron-like cells at P3 have outgrowing extensions (arrow) (e). These extensions contain bundles of microtubules, which run parallel to their long axis (arrow) (f). Endoplasmic reticulum (arrow) and vesicles (arrowhead) (g). Residual bodies (lipofuscin pigment granules) were present within the cytoplasm (arrow) (h). Bar in (a): 2 μm; bars in (b, c, d, f, h): 200 nm; bar in (e): 5 μm; bar in (g): 100 nm. EC-MSCs equine cadaver mesenchymal stem cells