Fig. 4

Bone marrow NSG mice reconstitution after transplantation of expanded HSPCs. a One month after transplantation, human hematopoietic cells were characterized in mice bone marrow by flow cytometry. Cell markers are presented in Table 1 (n = 4). *p <0.05. b The same analyses were performed 3 months after transplantation (n = 3). CLP common lymphoid progenitor cells, CMP common myeloid progenitor cells, GMP granulocyte macrophage progenitor cells, hi high, HSC hematopoietic stem cells, HSPC hematopoietic stem cell and progenitor cell, lo low, MEP megakaryocyte erythroid progenitor cells, MPP multipotent progenitor cells