Fig. 7

The effect of vascular endothelial growth factor (VEGF) (25 ng/ml and 100 ng/ml) on organotypic cultures of embryonic femurs (E11). a Micro computed tomography images. b Micro computed tomography analysis of bone volume (BV), bone surface/bone volume (BS/BV), bone volume/tissue volume (BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.No) and trabecular spacing (Tb.Sp) (n = 4 femurs per group). Significant differences compared to non-cultured femurs, *p ≤0.05, **p ≤0.01, ***p ≤0.001. Significant difference between basal and VEGF cultured femurs represent mean ± SD: #p ≤0.05, ^## p ≤0.01, ^### p ≤0.001