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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Exosomes secreted by human urine-derived stem cells could prevent kidney complications from type I diabetes in rats

Fig. 5

Intravenous injection of USCs-Exo could ameliorate the renal histopathology changes in diabetic rats at 12 weeks. Representative light microscope appearance of PAS staining in glomeruli. (a) normal, (b) diabetes, and (c) diabetes treated with USCs-Exo. Purple-red represents a positive region, suggesting mesangial matrix proliferation. (d) Quantitative analysis of mean mesangial area from each group of rats. Magnification 400×. Results are expressed as the means ± standard deviation. *P < 0.05, versus normal; # P < 0.05, versus diabetes. USCs-Exo Exosome from urine-derived stem cells

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Stem Cell Research & Therapy

ISSN: 1757-6512