microRNA-206 is involved in survival of hypoxia preconditioned mesenchymal stem cells through targeting Pim-1 kinase

Table 1 Groups used for the in-vitro and in-vivo experiments

Group^a	Step 1	Time (h)	Step 2	Time (h)
MSCs	Untreated
HP-MSCs	Untreated		Hypoxia exposure	12
HP-MSCs^miR-206	Transfected with miR-206 mimics	48	Hypoxia exposure	12
HP-MSCs^anti-miR-206	Transfected with miR-206 inhibitor	48	Hypoxia exposure	12
HP-MSCs^{anti-miR-206 + Pim-1 inhibitor}	Transfected with miR-206 inhibitor	48	Hypoxia with Pim-1 inhibitor treatment	12

^aMSCs subjected to different combinations of treatment
Step 1 first step of treatment, time length of treatment, Step 2 second step of treatment, MSC mesenchymal stem cell, HP-MSC mesenchymal stem cell subjected to hypoxic preconditioning, miR-206 microRNA-206

ISSN: 1757-6512