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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Periodontal regeneration in swine after cell injection and cell sheet transplantation of human dental pulp stem cells following good manufacturing practice

Fig. 4

Histopathological assessment of periodontal bone regeneration by H&E staining. New periodontal bone regeneration in the periodontal defects of the hDPSC injection group (a) and hDPSC sheet group (d). New bone was regenerated in the periodontal defect area in the hDPSC injection group (c) and hDPSC sheet group (f). The alveolar bone heights in the hDPSC sheet group and hDPSC injection group were much larger than those in the control group (i). B bone, C cementum, CEJ cemento-enameljunction, d dentin, HAB height of alveolar bone, hDPSC human dental pulp stem cell, PDL periodontal ligament, SE sulcular epithelium. However, deep periodontal pockets and shortages of new bone remainedin the control group (g). Much thicker sulcular epithelia and enlarged epithelial pegs were evident in the control group (h) compared with hDPSC injection (b) and hDPSC sheet group (e)

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