Table 2 Top 25 categories from a DAVID 6.7 analysis of cell surface proteins expressed on adipose-derived mesenchymal stromal cells
| Â | Constitutive | Proliferating | Confluent |
|---|---|---|---|
(n = 142, p > 0.05) | (n = 104, up >1.4-fold, p < 0.05) | (n = 79, up >1.4-fold, p < 0.05) | |
Rank | Category (enrichment score) | Category (enrichment score) | Category (enrichment score) |
1 | Membrane (48.26) | Signal (28.07) | Membrane (24.12) |
2 | Signal (47.47) | Membrane (27.82) | Signal (18.65) |
3 | Plasma membrane (28.33) | Cell adhesion (14.15) | Plasma membrane (11.82) |
4 | Cell adhesion (9.99) | Plasma membrane (12.38) | Tetraspanin (3.97) |
5 | Signal transduction (8.17) | Immunoglobulin-like (6.25) | Protease/peptidase (3.95) |
6 | Tetraspanin (7.20) | Tetraspanin (5.88) | ABC transporter (3.93) |
7 | Lipoprotein (5.52) | Integrin (5.75) | Growth factor binding (3.82) |
8 | Angiogenesis (5.11) | Response to wounding (4.85) | Cell adhesion (3.39) |
9 | B cell activation/Fas pathway (5.08) | Immunoglobulin-like V set (4.57) | Secreted (3.30) |
10 | Cell migration (4.86) | Metalloprotease (4.47) | Semaphorin (2.95) |
11 | Apoptosis (4.68) | Cell–cell adhesion (4.37) | Immunoglobulin-like (2.95) |
12 | Semaphorin (4.63) | Transferase (3.71) | Immune cell activation (2.55) |
13 | Immune response (4.38) | Semaphorin/integrin (3.56) | Vesicle-mediated transport (2.40) |
14 | Calcium-mediated signaling (4.20) | Transport (3.40) | Cytokine–cytokine receptor interaction (2.33) |
15 | Cytokine binding (4.12) | Extracellular matrix-receptor interaction (3.37) | Cell migration (2.29) |
16 | Activation immune response (4.00) | Cell motion (3.36) | Integrin (2.24) |
17 | Cell motion (3.68) | Differentiation (3.04) | Glycoprotein metabolic process (2.07) |
18 | Protein kinase cascade (3.64) | Epidermal growth factor (2.88) | Cell proliferation (1.96) |
19 | Integrin (3.31) | Low-density lipoprotein (2.32) | Membrane fraction (1.93) |
20 | Tyrosine protein kinase (3.04) | Biosynthetic process (2.20) | Immunoglobulin V-set (1.84) |
21 | Immune cell activation (3.02) | Secreted (2.13) | Regulation of transcription (1.56) |
22 | Signal-anchor (3.01) | Immune response (2.11) | Response to wounding (1.48) |
23 | Low density lipoprotein receptor (2.91) | Membrane fraction (2.04) | Regulation of immune activation (1.38) |
24 | Stress-activated protein kinase (2.90) | Magnesium ion binding (1.92) | Protein kinase cascade (1.18) |
25 | Wnt receptor pathway (2.88) | Cytokine binding (1.75) | Carbohydrate binding (1.07) |