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Table 2 Top 25 categories from a DAVID 6.7 analysis of cell surface proteins expressed on adipose-derived mesenchymal stromal cells

From: Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production

  Constitutive Proliferating Confluent
(n = 142, p > 0.05) (n = 104, up >1.4-fold, p < 0.05) (n = 79, up >1.4-fold, p < 0.05)
Rank Category (enrichment score) Category (enrichment score) Category (enrichment score)
1 Membrane (48.26) Signal (28.07) Membrane (24.12)
2 Signal (47.47) Membrane (27.82) Signal (18.65)
3 Plasma membrane (28.33) Cell adhesion (14.15) Plasma membrane (11.82)
4 Cell adhesion (9.99) Plasma membrane (12.38) Tetraspanin (3.97)
5 Signal transduction (8.17) Immunoglobulin-like (6.25) Protease/peptidase (3.95)
6 Tetraspanin (7.20) Tetraspanin (5.88) ABC transporter (3.93)
7 Lipoprotein (5.52) Integrin (5.75) Growth factor binding (3.82)
8 Angiogenesis (5.11) Response to wounding (4.85) Cell adhesion (3.39)
9 B cell activation/Fas pathway (5.08) Immunoglobulin-like V set (4.57) Secreted (3.30)
10 Cell migration (4.86) Metalloprotease (4.47) Semaphorin (2.95)
11 Apoptosis (4.68) Cell–cell adhesion (4.37) Immunoglobulin-like (2.95)
12 Semaphorin (4.63) Transferase (3.71) Immune cell activation (2.55)
13 Immune response (4.38) Semaphorin/integrin (3.56) Vesicle-mediated transport (2.40)
14 Calcium-mediated signaling (4.20) Transport (3.40) Cytokine–cytokine receptor interaction (2.33)
15 Cytokine binding (4.12) Extracellular matrix-receptor interaction (3.37) Cell migration (2.29)
16 Activation immune response (4.00) Cell motion (3.36) Integrin (2.24)
17 Cell motion (3.68) Differentiation (3.04) Glycoprotein metabolic process (2.07)
18 Protein kinase cascade (3.64) Epidermal growth factor (2.88) Cell proliferation (1.96)
19 Integrin (3.31) Low-density lipoprotein (2.32) Membrane fraction (1.93)
20 Tyrosine protein kinase (3.04) Biosynthetic process (2.20) Immunoglobulin V-set (1.84)
21 Immune cell activation (3.02) Secreted (2.13) Regulation of transcription (1.56)
22 Signal-anchor (3.01) Immune response (2.11) Response to wounding (1.48)
23 Low density lipoprotein receptor (2.91) Membrane fraction (2.04) Regulation of immune activation (1.38)
24 Stress-activated protein kinase (2.90) Magnesium ion binding (1.92) Protein kinase cascade (1.18)
25 Wnt receptor pathway (2.88) Cytokine binding (1.75) Carbohydrate binding (1.07)