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Table 1 Selected genes involved in adipogenic differentiation

From: TGFβ-induced switch from adipogenic to osteogenic differentiation of human mesenchymal stem cells: identification of drug targets for prevention of fat cell differentiation

Gene name Protein function Inhibitor Effect
ADAMTS5 Metalloproteinase Batimastat Positive
AGTR1 Angiotensin II receptor Losartan Negative
AKR1B10 Aldo-keto reductase Zopolrestat Positive
BDKRB2 Bradykinin receptor B2 Icatibant Negative
CXCL12 Chemokine SDF-1 (Not tested) (Not tested)
KCNK3 Potassium channel Doxapram Negative
PPARG Nuclear receptor GW9662 Positive
PRKAR2B cAMP protein kinase (Not tested) (Not tested)
VCAM1 Vascular cell adhesion (Not tested) (Not tested)
  1. Table presents the HUGO name, function, commercially available drug, and status of experimentally observed effects
  2. positive observed effect, negative no observed effect