Fig. 4
From: Hyaluronan induces odontoblastic differentiation of dental pulp stem cells via CD44
HA induces phosphorylation of Akt in DPSCs. a DPSCs were treated with HA (10 μg/mL) over a time course of 5–360 min, and then examined for phosphorylation of Akt and GSK3β by western blotting. b DPSCs were treated with HA (10 μg/mL) in the presence of LY294002 for 30 min, and the inhibition of Akt phosphorylation was validated. c Following inhibition of Akt phosphorylation by LY294002 treatment, DMP-1 expression was determined by western blotting. DMP-1 dentin matrix protein-1, HA hyaluronic acid