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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Local versus intravenous injections of skeletal muscle precursor cells in nonhuman primates with acute or chronic intrinsic urinary sphincter deficiency

Fig. 4

Resting MUP in monkeys with chronic ISD. Data are given as percent change in MUP from baseline values. The experimental groups are controls, chronic local vehicle (CLV), chronic local skeletal muscle precursor cell injection (CLM), or chronic systemic muscle cell injection (CSM). ANOVA p = 0.01; * = p < 0.05 vs. baseline and control at 6 months; § = p < 0.05 vs. baseline and control; # = p < 0.05 vs. CLV. All values are mean ± standard error of the mean (SEM). Results indicate that local (CLM), but not systemic (CSM) muscle cell treatment increased MUP values. However, cell therapy in chronic ISD was not as effective as in acute ISD (p < 0.05). MUP maximal urethral pressure, skMPC skeletal muscle precursor cells

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