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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Heme oxygenase-1-transduced bone marrow mesenchymal stem cells in reducing acute rejection and improving small bowel transplantation outcomes in rats

Fig. 7

Apoptotic cells in graft mucosae. a Histological sections from each rat group at each time point were subjected to TUNEL staining (magnification × 200). b Histogram showing the percentage of positive apoptotic signals in each group on days 1, 5, 7, and 10 (n = 5 in each group). Apoptotic cells in graft mucosae increased rapidly in the allogeneic control (Allo) group; the increase was significantly inhibited by both BMMSC and Ad/BMMSC treatment. TUNEL-positive apoptotic cells further decreased in the Ad/HO-1/BMMSC treatment group compared with the treatment control groups. Data expressed as mean ± SD (P < 0.05 compared with the allogeneic controls; # P < 0.05 compared with the BMMSC controls; $ P < 0.05 compared with the Ad/BMMSC controls). Ad adenoviral vector, BMMSC bone marrow mesenchymal stem cell, HO-1 heme oxygenase-1, TUNEL terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling

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Stem Cell Research & Therapy

ISSN: 1757-6512