Fig. 5
From: Human fetal and adult epicardial-derived cells: a novel model to study their activation
Fetal and adult EPDCs behave differently in tube formation assay. a Matrigel-based tube formation assay revealed that fetal EPDCs and sEPDCs failed to form tubes. In contrast, both adult EPDCs and sEPDCs were able to assemble in a network of tube-like structures. b Tubes expressed αSMA (scale bars: 100 μm). Tube formation is displayed as average length of tubes for (c) fetal and adult EPDCs and (d) their fully differentiated mesenchymal counterparts (sEPDCs). # p < 0.05. EPDCs epicardial-derived cells, sEPDCs spindle-shaped epicardial-derived cells