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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Characteristics of human adipose derived stem cells in scleroderma in comparison to sex and age matched normal controls: implications for regenerative medicine

Fig. 3

Quantitative RT-PCR analysis of osteogenic-, chondrogenic-, and adipogenic-specific genes expressed in ADSCs from SSc patients. Adipose-derived stem cells from systemic sclerosis patients (ADSC-SSc) have a similar gene expression profile following differentiation when compared to healthy control ADSCs (ADSC-N). a Fold-change in expression of the osteogenic genes collagen type 1 (ColI), alkaline phosphatase (ALP), and osteocalcin (OC) in ADSC-SSc and ADSC-N. b Fold-change in gene expression of the chondrogenic genes aggrecan (Agg) and collagen type II (ColII) in ADSC-SSc and ADSC-N. c Fold-change in gene expression of the adipogenic genes fatty acid binding protein 4 (FABP4), peroxisome proliferator-activated receptor gamma (PPARγ), CCAAT/enhancer binding protein alpha (C/EBBPα), and lipoprotein lipase (LPL) in ADSC-SSc and ADSC-N. Gene expression profiling was carried out at 3 weeks following differentiation. Fold change was normalised to GAPDH (n=3)

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Stem Cell Research & Therapy

ISSN: 1757-6512