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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Characteristics of human adipose derived stem cells in scleroderma in comparison to sex and age matched normal controls: implications for regenerative medicine

Fig. 6

Analysis of the migration and invasion potential of ADSCs derived from SSc patients. Migration and invasion potential of adipose-derived stem cells from systemic sclerosis patients (ADSC-SSc) was reduced compared to healthy control ADSCs (ADSC-N) at all passages examined. a Cell migration was assessed by QCM 24-Well Colorometric Cell migration Assay. Cells were assessed at passage 1 (P1) to P4. Migration was assessed at 24 h. Migration of ADSC-SSc was significantly reduced at P1, P2, and P4 compared to healthy control ADSCs (p < 0.01) (n = 6). b Cell invasion was assessed by QCM ECMatrix Cell Invasion Assay. Cells were assessed at P1 to P4. Invasion was assessed at 24 h. Invasion of ADSC-SSc was significantly reduced at P1, P2, and P4 compared to healthy control ADSCs (p < 0.015) (n = 6). *p <0.05, **p < 0.01

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